FertilAid Resources and Scientific Literature
The Natural Choice in Fertility Supplements
 FertilAid for Men Clinical Study: Data from an independent, placebo-controlled, "gold standard" clinical study indicates that the use of the supplement, FertilAid for Men, resulted in marked improvements in male fertility and sperm health. Specifically, the results of this important study reveal that taking FertilAid for Men significantly increases "total normal sperm motility" - with a tendency toward an "increase in total mobile sperm count".
Conducted by reproductive endocrinologist, Dr. J.E. Ellington, and pharmacologist, Dr. G.D. Clifton, the randomized, double-blind FertilAid for Men study was conducted through 2006 over a three month period to determine the effects of FertilAid on Men with '"abnormal sperm parameters", as defined by the World Health Organization.
The results of the FertilAid study revealed a "significant improvement" in the number of motile sperm, or "total normal sperm motility". According to Dr. J.E. Ellington, "men with higher levels of motile, normally shaped sperm have shown better pregnancy outcomes in several [independent] studies."
To read more about this benchmark FertilAid Clinical Study - and how FertilAid can enhance sperm quality and male fertility health - please click here.
Read About These Important Topics:
Other Studies
National Center for Chronic Disease Prevention and Health Promotion, Center for Disease Control and Prevention, U.S. DHHS 1996 Assisted Reproductive Technology Success Rates: National Summary and Fertility Clinic Reports, December, 1998.
Mortimer D, Menkveld R. Sperm morphology assessment - Historical perspectives and current opinions. J Androl.2001; 22:192-205
Smith S, Pfeifer SM, Collins JA. Diagnosis and management of female infertility. JAMA 2003; 290:1767-1770.
Fraga CG et al. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci 1991; 88: 11003-06.
Dawson EB et al. Effects of ascorbic acid on male fertility. Ann N Y Acad Sci 1987; 498: 312-23.
Suleimen SA et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. Jour Androl 1996; 17: 530-37.
Kessopoulou E et al. A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated with male infertility. Fertil Steril 1995; 64: 825-31.
Vitali G. et al. Carnitine supplementation in human idiopathic asthenospermia: clinical results. Drugs Exp Clin Res 1995; 21: 157.
MacPherson SR et al. The effect of oral selenium supplementation on human sperm motility. Br. Jour Urology 1998; 82: 76-80.
Chen JC et al. Effect of panax notoginseng extracts on inferior sperm motility in vitro. Am J Chin. Med. 1999; 27(1): 123-8.
Chen JC et al. Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro. Am J Chin. Med. 2001; 29(1): 155-60.
Gonzales, GF et al. Lipidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 2001 Dec; 3(4): 301-3.
Tikkiwal M et al. Effect of zinc administration on seminal zinc and fertility of oligospermic males. Ind J Phys Pharm 1987; 31:30-34.
Takihara H et al. Zinc sulfate therapy for infertile males with or without varicocelectomy. Urology 1987; 29: 63-64.
Netter A et al. Effect of zinc administration on plasma testosterone, dihydrotestosterone and sperm count. Arch Androl 1981; 7: 69-73.
Irvine DS, Twigg J, Gordon E, et al. DNA integrity in human spermatozoa: relationship with semen quality. J Androl 2000; 27:33-44.
Spano M, Bonde JP, Hjollund HI, et al. Sperm chromatin damage impairs human fertility. Fertil Steril 2000; 73:43-50.
Sun J, Juirisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol of Reprod 1997; 56:602-607.
Agarwal A, Said TM. Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 2003; 9: 331-45
Amman W. Favorable effect of Agnus castus (Agnolyt) on amenorrhea. ZFA (Stuttgart). 1982 Feb 10;58(4):228-31.
Bayer R. Treatment of infertility with vitamin E. Int J Fertil 1960; 5:70–8.
Czeizel AE, Metneki J, Dudas I. The effect of preconceptional multivitamin supplementation on fertility. Internat J Vit Nutr Res 1996;66:55–8.
Gerhard I I, Patek A, Monga B, Blank A, Gorkow C. Women with fertility disorders benefited from V. agnus-castus obtaining more pregnancies then the placebo group. Forsch Komplementarmed. 1998;5(6):272-278.
Howard JM et al. Red cell magnesium and glutathione peroxidase in infertile women -- effects of oral supplementation with magnesium and selenium. Magnesium Research, 7(1):49-57, 1994 March.
Loch, E, et al. Diagnosis and treatment of dyshormonal menstrual periods in the general practice. Gynakol Praxis, 1990, 14(3):489-95.
Loch, EG. Gynaecology in practice - A sure choice of therapy. Tjherapiewoche, 1993, 43(48):2577-80.
Milewicz A, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H. Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Arzneimittelforschung. 1993 Jul;43(7):752-6.
Propping D, Katzorke T. Treatment of corpus luteum insufficiency. Zeitschr Allgemeinmedizin 1987;63:932–3.
Sieve BF. The clinical effects of a new B-complex factor, para-aminobenzoic acid, on pigmentation and fertility. South Med Surg 1942(March);104:135–139.
Czeizel AE, Toth M, Rockenbauer M. Population-based case control study of folic acid supplementation during pregnancy. Teratology 1996; 53:345–51.
Czeizel AE, Toth M, Rockenbauer M. Population-based case control study of folic acid supplementation during pregnancy. Teratology 1996; 53:345–51.
MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991;338(8760):131–7.
Mazza D. How folate can help prevent birth defects. Aust Fam Physician 28(7):719, 1999. PubMed
Mazza D. Preventing congenital malformations. Aust Fam Physician 28(7):717-8, 1999. PubMed
Ulrich M, Kristofferson K, et al. The influence of folic acid supplement on the outcome of pregnancies in the county of Funen in Denmark. Part III. Congenital anomalies. An observational study. Eur J Obstet Gynecol Reprod Biol 87(2):115-8; discussion 103-4, 1999. PubMed
Abnormal Folate Metabolism and Mutation in Methylenetetrahydrofolate Reductase Gene May Be Maternal Risk Factors for Down Syndrome; James, S. Jill, et al; American Journal For Clinical Nutrition, volume 70, number 4, October 1999
Loumbakis P, Anezinis P, Evangeliou A, Delakas D, Sbyrakis N, Cranidis A. Effect of L-carnitine in patients with asthenospermia. Eur Urol 1996;30(S2):255. Abstract 954.
Costa M, Canale D, Filicori MD, Iddio S, Lenzi A. L-carnitine in idiopathic asthenozoospermia: a multicenter study. Andrologia 1994 May;26(3):155-9.
Infante JP, Huszagh VA. Secondary carnitine deficiency and impaired docosahexaenoic (22:6n-3) acid synthesis: a common denominator in the pathophysiology of diseases of oxidative phosphorylation and beta-oxidation. FEBS Lett 2000;468(1):1-5.
Campaniello E, Petrarolo N, Meriggiola MC, Valdiserri A, Pareschi A, Ucci N, Flamigni C, Filicori M. Carnitine administration in asthenospermia [abstract]. In: IV Int Congress Andrology; 1989 May; Firenze. p. 14-18(5).
Muller-Tyl E, Lohninger A, Fischl F, Legenstein E, Staniek H, Kaiser E. Effects of carnitine on sperm count and motility. Fertilitat 1988;4(1):1-4.
Micic S, Mladenovic I, Genbacev O. Does L-carnitine administered in vivo improve sperm motility? ARTA 1995;7:127-30.
Micic S. Effects of L-carnitine on sperm motility and number in infertile men [abstract]. In: 16th World Congress on Fertility and Sterility; 1998 Oct 4; San Francisco (CA).
Vicari, E. Effectiveness of short-term anti-oxidant high-dose therapy on IVF program outcome in infertile male patients with previous excessive sperm radical oxygen species production persistent even following antimicrobials administered for epididymitis: preliminary results. In: Ambrosini A, Melis GB, Dallapria S, Dessole S, editors. Infertility and assisted reproductive technology: from research to therapy. Bologna: Monduzzi Editore; 1997. p. 93-7.
Micic S, Lalic N, Bojanic N, Nale DJ. Carnitine therapy of oligospermic men [abstract]. In: J Androl 25th Annual Meeting program and abstracts; 2000 May 7-11; Boston: American Society of Andrology; 2000. p. 68. Abstract no. 135./li
Aitken RJ. The role of free oxygen radicals and sperm production. Int Jour Androl 1989; 12: 95-97
Zini A et al. Reactive oxygen species in semen of infertile patients. Int Jour Androl 1993; 16: 183-88.
Tikkiwal M et al. Effect of zinc administration on seminal zinc and fertility of oligospermic males. Ind J Phys Pharm 1987; 31:30-34.
Takihara H et al. Zinc sulfate therapy for infertile males with or without varicocelectomy. Urology 1987; 29: 63-64.
Netter A et al. Effect of zinc administration on plasma testosterone, dihydrotestosterone and sperm count. Arch Androl 1981; 7: 69-73.
Wallock, LM, Ames, BN. Adequate folic acid in diet may be important for both men and women of reproductive age. Ascribe Newswire, University of California, Berkley, 2001 Feb.
Fraga CG et al. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci 1991; 88: 11003-06.
Dawson EB et al. Effects of ascorbic acid on male fertility. Ann N Y Acad Sci 1987; 498: 312-23.
Suleimen SA et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. Jour Androl 1996; 17: 530-37.
Kessopoulou E et al. A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated with male infertility. Fertil Steril 1995; 64: 825-31.
Vitali G. et al. Carnitine supplementation in human idiopathic asthenospermia: clinical results. Drugs Exp Clin Res 1995; 21: 157.
MacPherson SR et al. The effect of oral selenium supplementation on human sperm motility. Br. Jour Urology 1998; 82: 76-80.
Common Mispellings of FertilAid: Fertilaide, Fertil Aide, Fertile Aid, Fertil Aid, Fertillity Aid, FertilAde, FertileAid, FertileAide
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